Increased water production costs and lower final water quality are consequences of membrane biofouling in nanofiltration and Reverse Osmosis (RO) applications which is largely controlled by disinfection of the feedwaters, however this approach has been unsuccessful in stopping the formation of biofilm on membrane surfaces. This article highlights alternative methods for biofouling control including the incorporation of 2-aminoimidazoles into the membrane matrix and outlines the specific objectives of this research.